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LMAN2L/VIPL Rabbit pAb
- 产品详情
- 实验流程
Application 
| IHC-P, IHC-F, IF, E |
|---|---|
| Primary Accession | Q9H0V9 |
| Other Accession | Q9H0V9 |
| Predicted | Rat, Pig, Human, Mouse, Rabbit, Dog, Horse, Sheep |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 39711 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human LMAN2L/VIPL |
| Epitope Specificity | 45-140/348 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Contains 1 L-type lectin-like domain. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | Lectin mannose-binding 1, also designated vesicular integral-membrane protein (VIP36), and lectin mannose-binding 2, also designated ERGIC-53, comprise a family of membrane bound, ubiquitously expressed proteins involved in the selective transport of newly synthesized glycoproteins from the endoplasmic reticulum to the ER-Golgi intermediate compartment. VIPL (VIP36-like protein), also known as LMAN2L (lectin, mannose-binding 2-like), is a 348 amino acid single-pass type I membrane protein that localizes to the endoplasmic reticulum and Golgi apparatus. Containing one L-type lectin-like domain, VIPL is highly expressed in skeletal muscle and kidney, and is found at intermediate levels in heart, liver and placenta, and low levels in brain, thymus, spleen, small intestine and lung. VIPL is suggested to be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. VIPL may function as a regulator of ERGIC-53. VIPL exists a two alternatively spliced isoforms. |
| Gene ID | 81562 |
|---|---|
| Other Names | MRD69; MRT52; VIPL; A630028F14Rik; VIP36-like; LMA2L_HUMAN; LMAN2L; Lectin mannose-binding 2-like (LMAN2-like protein); LMA2L_MOUSE; lectin, mannose binding 2 like; lectin, mannose-binding 2-like |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | LMAN2L |
|---|---|
| Synonyms | VIPL |
| Function | May be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. May function as a regulator of ERGIC-53. |
| Cellular Location | Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Note=Predominantly found in the endoplasmic reticulum. Partly found in the Golgi |
| Tissue Location | Expressed in numerous tissues. Highest expression in skeletal muscle and kidney, intermediate levels in heart, liver and placenta, low levels in brain, thymus, spleen, small intestine and lung. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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