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Iroquois homeobox protein 3 Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB, IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | P78415 |
| Other Accession | P78415 |
| Reactivity | Rat, Mouse |
| Predicted | Pig, Human, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 52119 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human Iroquois homeobox protein 3 |
| Epitope Specificity | 401-501/501 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the TALE/IRO homeobox family.Contains 1 homeobox DNA-binding domain. |
| SUBUNIT | Belongs to the TALE/IRO homeobox family.Contains 1 homeobox DNA-binding domain. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells. |
| Gene ID | 79191 |
|---|---|
| Other Names | IRX-1; IRXB1; IRX3_HUMAN; IRX3; Homeodomain protein IRXB1; Iroquois homeobox protein 3; iroquois homeobox 3 |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | IRX3 |
|---|---|
| Synonyms | IRXB1 |
| Function | Transcription factor involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells. Acts as a regulator of energy metabolism. |
| Cellular Location | Nucleus. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,250.00
Cat# AP99367
