癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
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CDC42EP3 Rabbit pAb
- 产品详情
- 实验流程
Application 
| IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | Q9UKI2 |
| Other Accession | Q9UKI2 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 27678 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human CDC42EP3 |
| Epitope Specificity | 11-110/254 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the BORG/CEP family.Contains 1 CRIB domain. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | CDC42EP3 is probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. It induces pseudopodia formation in fibroblasts. |
| Gene ID | 10602 |
|---|---|
| Other Names | BORG2; CEP3; UB1; BORG2_HUMAN; CDC42EP3; Binder of Rho GTPases 2; MSE55-related Cdc42-binding protein; CDC42 effector protein 3; CDC42 effector protein (Rho GTPase binding) 3 |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | CDC42EP3 |
|---|---|
| Synonyms | BORG2, CEP3 |
| Function | Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts. |
| Cellular Location | Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton |
| Tissue Location | Highly expressed in the heart and weakly in the brain. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,250.00
Cat# AP99597
