癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
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phospho-KLF5 (Ser272) Rabbit pAb
- 产品详情
- 实验流程
Application 
| IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | Q13887 |
| Other Accession | Q13887 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 50792 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthesised phosphopeptide derived from human KLF5 around the phosphorylation site of Ser272 |
| Epitope Specificity | PP(p-S)PP |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 3 C2H2-type zinc fingers. |
| SUBUNIT | Interacts with WWP1. |
| Post-translational modifications | Ubiquitinated. Polyubiquitination involves WWP1 and leads to proteasomal degradation of this protein. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. Since the protein localizes to the nucleus and binds the epidermal growth factor response element, it is thought to be a transcription factor. [provided by RefSeq, Jul 2008] |
| Gene ID | 688 |
|---|---|
| Other Names | BTEB2; CKLF; IKLF; 4930520J07Rik; KLF5_HUMAN; KLF5; Basic transcription element-binding protein 2 (BTE-binding protein 2); Colon krueppel-like factor; GC-box-binding protein 2; Intestinal-enriched krueppel-like factor; Transcription factor BTEB2; KLF5_MOUSE; KLF transcription factor 5; Kruppel-like factor 5 (intestinal); Kruppel like factor 5; intestinal Kruppel-like factor; KLF5 (phospho-S272); p-KLF5; phospho-KLF5; KLF5 (phospho-Ser272) |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | KLF5 |
|---|---|
| Synonyms | BTEB2, CKLF, IKLF |
| Function | Transcription factor that binds to GC box promoter elements. Activates the transcription of these genes. |
| Cellular Location | Nucleus. |
| Tissue Location | Expressed only in testis and placenta. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,250.00
Cat# AP99698
