癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Human CD63 Mouse mAb
- 产品详情
- 实验流程
| Reactivity | Human |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Calculated MW | 26 KDa |
| Physical State | Liquid |
| Isotype | Mouse IgG1, k |
| Purity | affinity purified by Protein G |
| Buffer | 0.01M PBS (pH7.4). |
| SIMILARITY | Belongs to the tetraspanin (TM4SF) family. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012] |
| Other Names | AD1; HOP-26; ME491; MLA1; OMA81H; Pltgp40; TSPAN30; CD63_HUMAN; CD63; Granulophysin; Lysosomal-associated membrane protein 3 (LAMP-3); Lysosome integral membrane protein 1 (Limp1); Melanoma-associated antigen ME491; Ocular melanoma-associated antigen; Tetraspanin-30 (Tspan-30); CD63 molecule; CD63 antigen (melanoma 1 antigen); AD1 antigen |
|---|---|
| Dilution | Flow-Cyt=1 µg/Test,ICC/IF=1:50-200 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| Name | Human CD63 Mouse mAb |
| Function | This antigen is associated with early stages of melanoma tumor progression. May play a role in growth regulation. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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