癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
SFT2B Rabbit pAb
- 产品详情
- 实验流程
Application 
| IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | O95562 |
| Other Accession | O95562 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 17779 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human SFT2B |
| Epitope Specificity | 1-100/160 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the SFT2 family. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | SFT2D2 is a 160 amino acid multi-pass membrane protein that belongs to the SFT2 family. SFT2D2 may be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. The SFT2D2 gene is conserved in dog, cow, mouse, rat, chicken, A.thaliana and rice, and maps to human chromosome 1q24.2. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. |
| Gene ID | 375035 |
|---|---|
| Other Names | UNQ512; dJ747L4.C1.2; 2010005O13Rik; cI-45; RGD1310623; SFT2B_HUMAN; SFT2D2; SFT2 domain-containing protein 2; SFT2B_MOUSE; SFT2B_RAT; SFT2 domain containing 2 |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | SFT2D2 {ECO:0000312|EMBL:AAH68098.1} |
|---|---|
| Function | May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. |
| Cellular Location | Membrane; Multi-pass membrane protein |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,250.00
Cat# AP99811
