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GTF2A1 alpha Rabbit pAb
- 产品详情
- 实验流程
Application 
| IHC-P, IHC-F, IF, E |
|---|---|
| Primary Accession | P52655 |
| Other Accession | P52655 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 41514 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human GTF2A1 alpha |
| Epitope Specificity | 1-100/376 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the TFIIA subunit 1 family. |
| Post-translational modifications | The alpha and beta subunits are postranslationally produced from the precursor form by TASP1. The cleavage promotes proteasomal degradation. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and several general initiation factors (summarized by DeJong and Roeder, 1993 [PubMed 8224848]). One of these factors is TFIIA, which when purified from HeLa extracts consists of 35-, 19-, and 12-kD subunits.[supplied by OMIM, Jul 2010] |
| Gene ID | 2957 |
|---|---|
| Other Names | TF2A1; TFIIA; TFIIA-42; TFIIAL; 6330549H03Rik; TfIIAa/b; Tfiia1; Tf2a; TF2AA_HUMAN; GTF2A1; General transcription factor IIA subunit 1; Transcription initiation factor TFIIA 42 kDa subunit (TFIIA-42); TF2AA_MOUSE; TF2AA_RAT; glucose regulated protein, 58kD pseudogene; general transcription factor IIA, 1, 19/37kDa; general transcription factor IIA 1; TFIIA alpha/beta subunits |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | GTF2A1 |
|---|---|
| Synonyms | TF2A1 |
| Function | TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity. |
| Cellular Location | Nucleus. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,250.00
Cat# AP99816
