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STMN3 Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB, IHC-P, IHC-F, IF, E |
|---|---|
| Primary Accession | Q9NZ72 |
| Other Accession | Q9NZ72 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 21017 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human STMN3 |
| Epitope Specificity | 77-130/180 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the stathmin family. |
| SUBUNIT | Interacts with STAT3 (By similarity). |
| Post-translational modifications | N-terminal palmitoylation promotes specific anchoring to the cytosolic leaflet of Golgi membranes and subsequent vesicular trafficking along dendrites and axons. Neuronal Stathmins are substrates for palmitoyltransferases ZDHHC3, ZDHHC7 and ZDHHC15. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | STMN3 belongs to the stathmin/oncoprotein 18 family of microtubule-destabilizing phosphoproteins. It is similar to the SCG10 protein and is involved in signal transduction and regulation of microtubule dynamics. |
| Gene ID | 50861 |
|---|---|
| Other Names | SCLIP; 9330161A03Rik; STMN3_HUMAN; STMN3; SCG10-like protein; STMN3_MOUSE; Hippocampus abundant transcript 3; SCG10-related protein HiAT3; STMN3_RAT; stathmin 3; stathmin-like 3 |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | STMN3 |
|---|---|
| Synonyms | SCLIP |
| Function | Exhibits microtubule-destabilizing activity, which is antagonized by STAT3. |
| Cellular Location | Golgi apparatus. Cell projection, growth cone. Cell projection, axon. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9JHU6} |
| Tissue Location | Neuron specific. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,250.00
Cat# AP99878
