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LHB Rabbit pAb

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, IHC-F, IF, E
Primary Accession P01229
Other Accession P01229
Host Rabbit
Clonality Polyclonal
Calculated MW 15345 Da
Physical State Liquid
Immunogen KLH conjugated synthetic peptide derived from midlle of human LH beta
Epitope Specificity 51-120/141
Isotype IgG
Purity affinity purified by Protein A
Buffer 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SIMILARITY Belongs to the glycoprotein hormones subunit beta family.
SUBUNIT Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin.
DISEASE Hypogonadism LHB-related (HGON-LHB) [MIM:152780]: Characterized by infertility and pseudohermaphroditism. Note=The disease is caused by mutations affecting the gene represented in this entry.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Background Descriptions Luteinizing Hormone is a member of the glycoprotein hormone family. Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. Mutations in the Luteinizing Hormone (LHB) gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism.
Additional Information
Gene ID 3972
Other Names CGB4; HH23; LSH-B; LSH-beta; Gm29035; LH; LH-B; LSHB_HUMAN; LHB; Lutropin beta chain; Luteinizing hormone subunit beta (LH-B | LSH-B | LSH-beta); LSHB_MOUSE; LSHB_RAT; luteinizing hormone subunit beta; luteinizing hormone beta polypeptide; lutropin, beta chain; interstitial cell stimulating hormone, beta chain
Dilution WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
StorageStore at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name LHB
Function Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.
Cellular Location Secreted.
Tissue Location Pituitary gland.
Research Areas
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