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PRP18 homolog Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB, IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | Q99633 |
| Other Accession | Q99633 |
| Reactivity | Rat |
| Predicted | Pig, Human, Mouse, Rabbit, Zebrafish, Chicken, Dog, Horse, Sheep |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 39860 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human PRP18 homolog |
| Epitope Specificity | 281-342/342 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the PRP18 family. |
| SUBUNIT | Heterodimer with PPIH. Interacts with PRPF4 and with the spliceosome. Part of a complex containing U4/U6 snRNPs. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to the yeast splicing factor Prp18. [provided by RefSeq, Jul 2008] |
| Gene ID | 8559 |
|---|---|
| Other Names | PRP18; hPrp18; 2810441A10Rik; KCRF; Pprf18; PRP18_BOVIN; PRPF18; PRP18 homolog; PRP18_HUMAN; PRP18 homolog (hPRP18); PRP18_MOUSE; PRP18_RAT; Potassium channel regulatory factor; pre-mRNA processing factor 18; PRP18 pre-mRNA processing factor 18 homolog (yeast); PRP18 pre-mRNA processing factor 18 homolog (S. cerevisiae) |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | PRPF18 |
|---|---|
| Synonyms | HPRP18 |
| Function | Participates in the second step of pre-mRNA splicing. |
| Cellular Location | Nucleus speckle. Note=Colocalizes with spliceosomal snRNPs. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,980.00
Cat# AP99984
