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ACTH

Mouse Monoclonal Antibody (Mab)

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
IHC
Primary Accession P01189
Host Mouse
Clonality Monoclonal
Calculated MW 29424 Da
Additional Information
Gene ID 5443
Other Names Pro-opiomelanocortin, POMC, Corticotropin-lipotropin, NPP, Melanotropin gamma, Gamma-MSH, Potential peptide, Corticotropin, Adrenocorticotropic hormone, ACTH, Melanocyte-stimulating hormone alpha, Alpha-MSH, Melanotropin alpha, Corticotropin-like intermediary peptide, CLIP, Lipotropin beta, Beta-LPH, Lipotropin gamma, Gamma-LPH, Melanocyte-stimulating hormone beta, Beta-MSH, Melanotropin beta, Beta-endorphin, Met-enkephalin, POMC
Protein Information
Name POMC
Function [Corticotropin]: Stimulates the adrenal glands to release cortisol. [Melanocyte-stimulating hormone beta]: Increases the pigmentation of skin by increasing melanin production in melanocytes. [Met-enkephalin]: Endogenous opiate.
Cellular Location Secreted {ECO:0000250|UniProtKB:P01193}. Note=Melanocyte-stimulating hormone alpha and beta-endorphin are stored in separate granules in hypothalamic POMC neurons, suggesting that secretion may be under the control of different regulatory mechanisms {ECO:0000250|UniProtKB:P01193}
Tissue Location ACTH and MSH are produced by the pituitary gland.
Research Areas
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