Anti-IL-4 Reference Antibody (pascolizumab)
Recombinant Antibody
- 产品详情
- 实验流程
Application ![]()
| FC, Kinetics, Animal Model |
---|---|
Primary Accession | P24394 |
Reactivity | Human, Mouse |
Clonality | Monoclonal |
Isotype | IgG1 |
Calculated MW | 89658 Da |
Target/Specificity | IL-4 |
---|---|
Endotoxin | < 0.001EU/ µg,determined by LAL method. |
Conjugation | Unconjugated |
Expression system | CHO Cell |
Format | Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column. |
Name | IL4R |
---|---|
Synonyms | IL4RA |
Function | Receptor for both interleukin 4 and interleukin 13 (PubMed:17030238). Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2. |
Cellular Location | Cell membrane; Single-pass type I membrane protein |
Tissue Location | Isoform 1 and isoform 2 are highly expressed in activated T-cells |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.

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