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>   首页   >   产品   >   一抗   >   基因重组   >   Anti-IL-4 Reference Antibody (pascolizumab)   

Anti-IL-4 Reference Antibody (pascolizumab)

Recombinant Antibody

     
  • 1 - Anti-IL-4 Reference Antibody (pascolizumab) APR10688
    Anti-IL-4 Reference Antibody (pascolizumab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%
  • 1 - Anti-IL-4 Reference Antibody (pascolizumab) APR10688
    The purity of Anti-IL-4 Reference Antibody (pascolizumab)is more than 95% ,determined by SEC-HPLC.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
FC, Kinetics, Animal Model
Primary Accession P24394
Reactivity Human, Mouse
Clonality Monoclonal
Isotype IgG1
Calculated MW 89658 Da
Additional Information
Target/Specificity IL-4
Endotoxin < 0.001EU/ µg,determined by LAL method.
Conjugation Unconjugated
Expression system CHO Cell
Format Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column.
Protein Information
Name IL4R
Synonyms IL4RA
Function Receptor for both interleukin 4 and interleukin 13 (PubMed:17030238). Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Isoform 1 and isoform 2 are highly expressed in activated T-cells
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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