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Anti-Dysadherin Reference Antibody (Centrose patent anti-dysadherin)

Recombinant Antibody

Anti-Dysadherin Reference Antibody (Centrose patent anti-dysadherin) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 90%.
The purity of Anti-Dysadherin Reference Antibody (Centrose patent anti-dysadherin) is more than 95%, determined by SEC-HPLC.

产品详情
实验流程

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	Functional assay, Kinetics (SPR), Kinetics (BLI), FACS, E, FTA
Primary Accession	Q96DB9
Reactivity	Human
Clonality	Monoclonal
Isotype	IgG1
Calculated MW	19472 Da

Additional Information
Target/Specificity	Dysadherin
Endotoxin	< 0.001EU/ µg,determined by LAL method.
Conjugation	Unconjugated
Expression system	CHO
Format	Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column.

For Research Use Only. Not For Use In Diagnostic Procedures.

Patent Notice: The variable region sequence of this antibody is derived from a published third-party patent. This product is manufactured independently as a Research Use Only (RUO) reagent and is not licensed, sponsored, or endorsed by the patent holder. It is intended solely for research purposes. Customers considering any commercial, diagnostic, or therapeutic use should independently evaluate freedom-to-operate with respect to relevant third-party patents.

Protein Information
Name	FXYD5
Synonyms	DYSAD, IWU1
Function	Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane (By similarity). May increase NKA activity by increasing the apparent affinity for Na(+) (PubMed:18263667). Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis (PubMed:11756660).
Cellular Location	Cell membrane; Single-pass type I membrane protein {ECO:0000250\|UniProtKB:P97808} Basolateral cell membrane {ECO:0000250\|UniProtKB:P97808}; Single-pass type I membrane protein {ECO:0000250\|UniProtKB:P97808}. Note=In kidneys localizes to the basolateral membrane of the connecting tubule {ECO:0000250\|UniProtKB:P97808}

Research Areas

Application Protocols

Provided below are standard protocols that you may find useful for product applications.

Western Blot Protocol

Blocking Peptides Protocol

Dot Blot Protocol

Immunohistochemistry Protocol

Immunofluorescence Protocol

Immunoprecipitation Protocol

Flow Cytomety Protocol

Cell Culture Protocol