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Anti-UPK1B Reference Antibody (Macrogenics patent anti-UPK-1B)

Anti-UPK-1B Reference Antibody (Macrogenics patent anti-UPK-1B) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
The purity of Anti-UPK-1B Reference Antibody (Macrogenics patent anti-UPK-1B) is 99.27%, determined by SEC-HPLC.
RT-4 cells were stained with Macrogenics patent anti-UPK-1B and negative control protein respectively, washed and then followed by PE and analyzed with FACS, with the EC50 is 7.19 nM.

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实验流程

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	Functional assay, Kinetics (SPR), Kinetics (BLI), FACS, E, FTA
Primary Accession	O75841
Reactivity	Human
Clonality	Monoclonal
Isotype	IgG1
Calculated MW	29643 Da

Additional Information
Target/Specificity	UPK1B
Expression system	CHO

For Research Use Only. Not For Use In Diagnostic Procedures.

Patent Notice: The variable region sequence of this antibody is derived from a published third-party patent. This product is manufactured independently as a Research Use Only (RUO) reagent and is not licensed, sponsored, or endorsed by the patent holder. It is intended solely for research purposes. Customers considering any commercial, diagnostic, or therapeutic use should independently evaluate freedom-to-operate with respect to relevant third-party patents.

Protein Information
Name	UPK1B
Synonyms	TSPAN20
Function	Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions (By similarity).
Cellular Location	Membrane; Multi-pass membrane protein.
Tissue Location	Bladder epithelium.

Research Areas

Application Protocols

Provided below are standard protocols that you may find useful for product applications.

Western Blot Protocol

Blocking Peptides Protocol

Dot Blot Protocol

Immunohistochemistry Protocol

Immunofluorescence Protocol

Immunoprecipitation Protocol

Flow Cytomety Protocol

Cell Culture Protocol