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Anti-IL-1RA Reference Antibody (CNRS patent anti-IL-1RA)

Anti-IL-1RA Reference Antibody (CNRS patent anti-IL-1RA) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
The purity of Anti-IL-1RA Reference Antibody (CNRS patent anti-IL-1RA) is 100%, determined by SEC-HPLC.
Immobilized N-His-Hu-IL-1RA-ECD at 2 µg/mL can bind CNRS patent anti-IL-1RA, EC50= 0.005879 µg/mL.

产品详情
实验流程

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	Functional assay, Kinetics (SPR), Kinetics (BLI), FACS, E, FTA
Primary Accession	P18510
Reactivity	Human
Clonality	Monoclonal
Isotype	IgG1
Calculated MW	20055 Da

Additional Information
Target/Specificity	IL-1RA
Expression system	CHO

For Research Use Only. Not For Use In Diagnostic Procedures.

Patent Notice: The variable region sequence of this antibody is derived from a published third-party patent. This product is manufactured independently as a Research Use Only (RUO) reagent and is not licensed, sponsored, or endorsed by the patent holder. It is intended solely for research purposes. Customers considering any commercial, diagnostic, or therapeutic use should independently evaluate freedom-to-operate with respect to relevant third-party patents.

Protein Information
Name	IL1RN
Synonyms	IL1F3, IL1RA
Function	Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens.
Cellular Location	[Isoform 1]: Secreted [Isoform 3]: Cytoplasm.
Tissue Location	The intracellular form of IL1RN is predominantly expressed in epithelial cells

Research Areas

Application Protocols

Provided below are standard protocols that you may find useful for product applications.

Western Blot Protocol

Blocking Peptides Protocol

Dot Blot Protocol

Immunohistochemistry Protocol

Immunofluorescence Protocol

Immunoprecipitation Protocol

Flow Cytomety Protocol

Cell Culture Protocol