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Anti-EPO Reference Antibody (Amgen patent anti-EPO)

Anti-EPO Reference Antibody (Amgen patent anti-EPO) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
The purity of Anti-EPO Reference Antibody (Amgen patent anti-EPO) is 99.05%, determined by SEC-HPLC.
Immobilized hu-erythropoietin-His at 2 µg/mL can bind Amgen patent anti-EPO, EC50= 0.003299 µg/mL.

产品详情
实验流程

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	Functional assay, Kinetics (SPR), Kinetics (BLI), FACS, E, FTA
Primary Accession	P01588
Reactivity	Human
Clonality	Monoclonal
Isotype	IgG4SP-opti
Calculated MW	21307 Da

Additional Information
Target/Specificity	EPO
Expression system	CHO

For Research Use Only. Not For Use In Diagnostic Procedures.

Patent Notice: The variable region sequence of this antibody is derived from a published third-party patent. This product is manufactured independently as a Research Use Only (RUO) reagent and is not licensed, sponsored, or endorsed by the patent holder. It is intended solely for research purposes. Customers considering any commercial, diagnostic, or therapeutic use should independently evaluate freedom-to-operate with respect to relevant third-party patents.

Protein Information
Name	EPO
Function	Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass (PubMed:28283061). Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3 (PubMed:9774108).
Cellular Location	Secreted.
Tissue Location	Produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals.

Research Areas

Application Protocols

Provided below are standard protocols that you may find useful for product applications.

Western Blot Protocol

Blocking Peptides Protocol

Dot Blot Protocol

Immunohistochemistry Protocol

Immunofluorescence Protocol

Immunoprecipitation Protocol

Flow Cytomety Protocol

Cell Culture Protocol