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Anti-CLDN3 Reference Antibody (GSK patent anti-CLDN3 CAR)

Anti-CLDN3 Reference Antibody (GSK patent anti-CLDN3 CAR) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
The purity of Anti-CLDN3 Reference Antibody (GSK patent anti-CLDN3 CAR) is 99.7%, determined by SEC-HPLC.
huCLDN3-HEK293 cell line were stained with GSK patent anti-CLDN3 CAR and negative control protein respectively, washed and then followed by PE and analyzed with FACS, with the EC50 is 2.526 nM.

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Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	Functional assay, Kinetics (SPR), Kinetics (BLI), FACS, E, FTA
Primary Accession	O15551
Reactivity	Human
Clonality	Monoclonal
Isotype	IgG1
Calculated MW	23319 Da

Additional Information
Target/Specificity	CLDN3
Expression system	CHO

For Research Use Only. Not For Use In Diagnostic Procedures.

Patent Notice: The variable region sequence of this antibody is derived from a published third-party patent. This product is manufactured independently as a Research Use Only (RUO) reagent and is not licensed, sponsored, or endorsed by the patent holder. It is intended solely for research purposes. Customers considering any commercial, diagnostic, or therapeutic use should independently evaluate freedom-to-operate with respect to relevant third-party patents.

Protein Information
Name	CLDN3
Synonyms	C7orf1, CPETR2
Function	Barrier-forming claudin. Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Cellular Location	Cell junction, tight junction. Cell membrane; Multi-pass membrane protein

Research Areas

Application Protocols

Provided below are standard protocols that you may find useful for product applications.

Western Blot Protocol

Blocking Peptides Protocol

Dot Blot Protocol

Immunohistochemistry Protocol

Immunofluorescence Protocol

Immunoprecipitation Protocol

Flow Cytomety Protocol

Cell Culture Protocol