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Anti-AGR2 Reference Antibody (Shanghai Jiao Tong U. patent anti-AGR2)

Anti-AGR2 Reference Antibody (Shanghai Jiao Tong U. patent anti-AGR2) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
The purity of Anti-AGR2 Reference Antibody (Shanghai Jiao Tong U. patent anti-AGR2) is 99%, determined by SEC-HPLC.
Immobilized hu-AGR2-his at 2 µg/mL can bind Shanghai Jiao Tong U. patent anti-AGR2, EC50= 0.01594 µg/mL.

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Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	Functional assay, Kinetics (SPR), Kinetics (BLI), FACS, E, FTA
Primary Accession	O95994
Reactivity	Human
Clonality	Monoclonal
Isotype	IgG1
Calculated MW	19979 Da

Additional Information
Target/Specificity	AGR2
Expression system	CHO

For Research Use Only. Not For Use In Diagnostic Procedures.

Patent Notice: The variable region sequence of this antibody is derived from a published third-party patent. This product is manufactured independently as a Research Use Only (RUO) reagent and is not licensed, sponsored, or endorsed by the patent holder. It is intended solely for research purposes. Customers considering any commercial, diagnostic, or therapeutic use should independently evaluate freedom-to-operate with respect to relevant third-party patents.

Protein Information
Name	AGR2
Synonyms	AG2
Function	Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth. Promotes cell adhesion (PubMed:23274113).
Cellular Location	Secreted. Endoplasmic reticulum {ECO:0000250\|UniProtKB:O88312}
Tissue Location	Expressed strongly in trachea, lung, stomach, colon, prostate and small intestine. Expressed weakly in pituitary gland, salivary gland, mammary gland, bladder, appendix, ovary, fetal lung, uterus, pancreas, kidney, fetal kidney, testis, placenta, thyroid gland and in estrogen receptor (ER)-positive breast cancer cell lines

Research Areas

Application Protocols

Provided below are standard protocols that you may find useful for product applications.

Western Blot Protocol

Blocking Peptides Protocol

Dot Blot Protocol

Immunohistochemistry Protocol

Immunofluorescence Protocol

Immunoprecipitation Protocol

Flow Cytomety Protocol

Cell Culture Protocol