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Anti-IL-12RB2 Reference Antibody (Dualyx patent anti-IL-12RB2)

Anti-IL-12RB2 Reference Antibody (Dualyx patent anti-IL-12RB2) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
The purity of Anti-IL-12RB2 Reference Antibody (Dualyx patent anti-IL-12RB2) is 100%, determined by SEC-HPLC.
PLVX-puro-IL-12RB2-FL cell line were stained with Dualyx patent anti-IL-12RB2 and negative control protein respectively, washed and then followed by PE and analyzed with FACS, with the EC50 is 0.133 nM.

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实验流程

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	Functional assay, Kinetics (SPR), Kinetics (BLI), FACS, E, FTA
Primary Accession	Q99665
Reactivity	Human
Clonality	Monoclonal
Isotype	IgG1-CS
Calculated MW	97135 Da

Additional Information
Target/Specificity	IL-12RB2
Expression system	CHO

For Research Use Only. Not For Use In Diagnostic Procedures.

Patent Notice: The variable region sequence of this antibody is derived from a published third-party patent. This product is manufactured independently as a Research Use Only (RUO) reagent and is not licensed, sponsored, or endorsed by the patent holder. It is intended solely for research purposes. Customers considering any commercial, diagnostic, or therapeutic use should independently evaluate freedom-to-operate with respect to relevant third-party patents.

Protein Information
Name	IL12RB2
Function	Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production.
Cellular Location	Membrane; Single-pass type I membrane protein.
Tissue Location	Isoform 2 is expressed at similar levels in both naive and activated T-cells.

Research Areas

Application Protocols

Provided below are standard protocols that you may find useful for product applications.

Western Blot Protocol

Blocking Peptides Protocol

Dot Blot Protocol

Immunohistochemistry Protocol

Immunofluorescence Protocol

Immunoprecipitation Protocol

Flow Cytomety Protocol

Cell Culture Protocol