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Anti-KLRG1 Reference Antibody (Ulviprubart）

Anti-KLRG1 Reference Antibody (Ulviprubart) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
The purity of Anti-KLRG1 Reference Antibody (Ulviprubart) is 96.2%, determined by SEC-HPLC.
KG-1 cells were stained with Ulviprubart and negative control protein respectively, washed and then followed by PE and analyzed with FACS, with the EC50 is 57.90 nM.

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Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	Functional assay, Kinetics (SPR), Kinetics (BLI), FACS, E, FTA
Primary Accession	Q96E93
Reactivity	Human
Clonality	Monoclonal
Isotype	IgG1-EM
Calculated MW	21831 Da

Additional Information
Target/Specificity	KLRG1
Expression system	CHO

For Research Use Only. Not For Use In Diagnostic Procedures.

Patent Notice: The variable region sequence of this antibody is derived from a published third-party patent. This product is manufactured independently as a Research Use Only (RUO) reagent and is not licensed, sponsored, or endorsed by the patent holder. It is intended solely for research purposes. Customers considering any commercial, diagnostic, or therapeutic use should independently evaluate freedom-to-operate with respect to relevant third-party patents.

Protein Information
Name	KLRG1
Synonyms	CLEC15A, MAFA, MAFAL
Function	Plays an inhibitory role on natural killer (NK) cells and T- cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E- cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.
Cellular Location	Cell membrane; Single-pass type II membrane protein
Tissue Location	Expressed specifically on natural killer (NK) cells and T-cells, mainly CD8 T-cells.

Research Areas

Application Protocols

Provided below are standard protocols that you may find useful for product applications.

Western Blot Protocol

Blocking Peptides Protocol

Dot Blot Protocol

Immunohistochemistry Protocol

Immunofluorescence Protocol

Immunoprecipitation Protocol

Flow Cytomety Protocol

Cell Culture Protocol