> 首页 > 产品 > 一抗 > 其他 > Anti-Integrin alpha 9 Reference Antibody (ASP5094)

Anti-Integrin alpha 9 Reference Antibody (ASP5094)

Anti-Integrin alpha 9 Reference Antibody (ASP5094) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
The purity of Anti-Integrin alpha 9 Reference Antibody (ASP5094) is 98.78%, determined by SEC-HPLC.
PLVX-puro-Integrin alpha 9-FL cell line were stained with ASP5094 and negative control protein respectively, washed and then followed by PE and analyzed with FACS, with the EC50 is 0.204 nM.

产品详情
实验流程

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	Functional assay, Kinetics (SPR), Kinetics (BLI), FACS, E, FTA
Primary Accession	Q13797
Reactivity	Human
Clonality	Monoclonal
Isotype	IgG1
Calculated MW	114489 Da

Additional Information
Target/Specificity	Integrin alpha 9
Expression system	CHO

For Research Use Only. Not For Use In Diagnostic Procedures.

Patent Notice: The variable region sequence of this antibody is derived from a published third-party patent. This product is manufactured independently as a Research Use Only (RUO) reagent and is not licensed, sponsored, or endorsed by the patent holder. It is intended solely for research purposes. Customers considering any commercial, diagnostic, or therapeutic use should independently evaluate freedom-to-operate with respect to relevant third-party patents.

Protein Information
Name	ITGA9
Function	Integrin alpha-9/beta-1 (ITGA9:ITGB1) is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D- G-I-E-L in cytotactin. ITGA9:ITGB1 may play a crucial role in SVEP1/polydom-mediated myoblast cell adhesion (By similarity). Integrin ITGA9:ITGB1 represses PRKCA-mediated L-type voltage-gated channel Ca(2+) influx and ROCK-mediated calcium sensitivity in vascular smooth muscle cells via its interaction with SVEP1, thereby inhibiting vasocontraction (PubMed:35802072).
Cellular Location	Membrane; Single-pass type I membrane protein
Tissue Location	Expressed in vascular smooth muscle cells (at protein level) (PubMed:35802072). Expressed in the airway epithelium (at protein level) (PubMed:8245132).

Research Areas

Application Protocols

Provided below are standard protocols that you may find useful for product applications.

Western Blot Protocol

Blocking Peptides Protocol

Dot Blot Protocol

Immunohistochemistry Protocol

Immunofluorescence Protocol

Immunoprecipitation Protocol

Flow Cytomety Protocol

Cell Culture Protocol