癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
OVGP1 Antibody
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IF, ICC, E |
|---|---|
| Primary Accession | Q12889 |
| Other Accession | NP_002548, 58386720 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 75421 Da |
| Concentration (mg/ml) | 1 mg/mL |
| Conjugate | Unconjugated |
| Application Notes | OVGP1 antibody can be used for the detection of OVGP1 by Western blot at 1 µg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 µg/mL. For immunofluorescence start at 2.5 µg/mL. |
| Gene ID | 5016 |
|---|---|
| Other Names | Oviduct-specific glycoprotein, Estrogen-dependent oviduct protein, Mucin-9, Oviductal glycoprotein, Oviductin, OVGP1, MUC9, OGP |
| Target/Specificity | OVGP1; |
| Reconstitution & Storage | OVGP1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Precautions | OVGP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | OVGP1 |
|---|---|
| Synonyms | MUC9, OGP |
| Function | Binds to oocyte zona pellucida in vivo. May play a role in the fertilization process and/or early embryonic development. |
| Cellular Location | Cytoplasmic vesicle, secretory vesicle. Note=Secretory granules |
| Tissue Location | Oviduct. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
OVGP1 Antibody: Oviductins belong to a family of glycoproteins that have been suggested to play several roles during the early processes of reproduction. OVGP1 is a large carbohydrate-rich, epithelial glycoprotein with numerous O-glycosylation sites within threonine, serine, and proline-rich tandem repeats. The protein is secreted from non-ciliated oviductal epithelial cells and associates with ovulated oocytes, blastomeres, and spermatozoan acrosomal regions. At least two isoforms of OVGP are known to exist.
REFERENCES
Buhi WC. Characterization and biological roles of oviduct-specific, oestrogen-dependent glycoprotein. Reproduction123:355-62.
Arias EB, Verhage HG and Jaffe RC. Complementary deoxyribonucleic acid cloning and molecular characterization of an estrogen-dependent human oviductal glycoprotein. Biol. Reprod.1994; 51:685-94.
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