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NIPSNAP3B Antibody

     
  • 1 - NIPSNAP3B Antibody ASC10821
    Western blot analysis of NIPSNAP3B in mouse brain tissue lysate with NIPSNAP3B antibody at (A) 1 and (B) 2 µg/mL.
  • 2 - NIPSNAP3B Antibody ASC10821
    Immunohistochemistry of NIPSNAP3B in mouse brain tissue with NIPSNAP3B antibody at 2.5 µg/mL.
  • 3 - NIPSNAP3B Antibody ASC10821
    Immunofluorescence of NIPSNAP3B in mouse brain tissue with NIPSNAP3B antibody at 5 µg/mL.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IF, E, IHC-P
Primary Accession Q9BS92
Other Accession Q9BS92, 17380145
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 28313 Da
Concentration (mg/ml) 1 mg/mL
Conjugate Unconjugated
Application Notes NIPSNAP3B antibody can be used for detection of NIPSNAP3B by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 5 µg/mL.
Additional Information
Gene ID 55335
Other Names Protein NipSnap homolog 3B, NipSnap3B, SNAP1, NIPSNAP3B, NIPSNAP3
Target/Specificity NIPSNAP3B; NIPSNAP3B antibody is predicted to not cross-react with any other members of the NIPSNAP protein family.
Reconstitution & Storage NIPSNAP3B antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsNIPSNAP3B Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NIPSNAP3B
Synonyms NIPSNAP3
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

NIPSNAP3B Antibody: The NIPSNAP proteins comprise a family of evolutionarily well-conserved proteins with strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. NIPSNAP2, a novel gene encoding a protein with tyrosine phosphorylation sites and a transmembrane domain, is co-amplified with EGFR in approximately 40% of glioblastomas, the most common and malignant form of central nervous system tumors. While NIPSNAP3B is highly expressed skeletal muscle, NIPSNAP3A mRNA levels are low. NIPSNAP proteins have been suggested to be important in vesicular transport.

REFERENCES

Seroussi E, Pan HQ, Kedra D, et al. Characterization of the human NIPSNAP1 gene from 22q12: a member of a novel gene family. Gene1998; 212:13-20.
Wang X-Y, Smith DI, Liu W, et al. GBAS, a novel gene encoding a protein with tyrosine phosphorylation sites and a transmembrane domain, is co-amplified with EGFR. Genomics1998; 49:448-51.
Buechler C, Bodzioch M, Bared SM, et al. Expression pattern and raft association of NIPSNAP3 and NIPSNAP4, highly homologous proteins encoded by genes in close proximity to the ATP-binding cassette transporter A1. Genomics2004; 83:1116-24.

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