癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
ZBED2 Antibody
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, ICC, E |
|---|---|
| Primary Accession | Q9BTP6 |
| Other Accession | NP_078784, 56790947 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 25122 Da |
| Concentration (mg/ml) | 1 mg/mL |
| Conjugate | Unconjugated |
| Application Notes | ZBED2 antibody can be used for detection of ZBED2 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunocytochemistry starting at 5 µg/mL. |
| Gene ID | 79413 |
|---|---|
| Other Names | Zinc finger BED domain-containing protein 2, ZBED2 |
| Target/Specificity | ZBED2; This antibody is predicted to have no cross-reactivity to ZBED1 or ZBED3. |
| Reconstitution & Storage | ZBED2 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Precautions | ZBED2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | ZBED2 |
|---|---|
| Function | Transcriptional regulator which has intrinsic repressor activity and which competes with the transcriptional activator IRF1 for binding to the 5'-[CA]GAA[AC]C[CT]-3' consensus sequence in gene promoters (PubMed:32385160). May thereby play a role in keratinocyte differentiation (PubMed:31552090). |
| Cellular Location | Nucleus. |
| Tissue Location | Expressed in keratinocytes. |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
ZBED2 Antibody: The ZBED2 protein possesses a BED-type zinc finger, a 50 to 60 amino acid domain that contains a characteristic motif with two highly conserved aromatic positions, as well as a shared pattern of cysteines and histidines that is predicted to form the zinc finger. ZBED2 was identified through a screening of 37 human gastric cancer cDNA libraries. While the function of this protein unknown at this time, the presence of the zinc finger suggests that it may have DNA or RNA binding properties.
REFERENCES
Oh J-H, Yang JO, Hahn Y, et al. Transcriptome analysis of human gastric cancer. Mamm. Genome2005; 16:942-54.
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