癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
SLAIN1 Antibody
- 产品详情
- 实验流程
- 背景知识
Application 
| E, IHC-P |
|---|---|
| Primary Accession | Q8ND83 |
| Other Accession | NP_002456, 338968860 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 60595 Da |
| Concentration (mg/ml) | 1 mg/mL |
| Conjugate | Unconjugated |
| Application Notes | SLAIN1 antibody can be used for detection of SLAIN1 by immunohistochemistry at 5 µg/mL. |
| Gene ID | 122060 |
|---|---|
| Other Names | SLAIN motif-containing protein 1, SLAIN1, C13orf32 |
| Target/Specificity | SLAIN1; At least three isoforms of SLAIN1 are known to exist; this antibody will detect only the largest isoform. SLAIN1 antibody is predicted not to cross-react with SLAIN2. |
| Reconstitution & Storage | SLAIN1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Precautions | SLAIN1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | SLAIN1 |
|---|---|
| Synonyms | C13orf32 |
| Function | Microtubule plus-end tracking protein that might be involved in the regulation of cytoplasmic microtubule dynamics, microtubule organization and microtubule elongation. |
| Cellular Location | Cytoplasm, cytoskeleton. Note=Colocalizes with microtubules Detected at the plus end of growing microtubules |
| Tissue Location | Expressed in embryonic stem cells (PubMed:16546155). Expressed in brain (PubMed:21646404) |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
SLAIN1 Antibody: SLAIN1 is a novel stem cell protein that was identified by transciptional profiling of mouse and human embryonic stem cells (ESCs) and is expressed at the stem cell and epiblast stages. Unlike its more widely expressed homolog SLAIN2, SLAIN1 was found to be expressed in the epiblast, nervous system, tailbud and somites of the developing mouse embryo later experiments suggested that SLAIN1 may play a role in the development of the nervous system as well as in the morphogenesis of several embryonic structures.
REFERENCES
Hirst CE, Ng ES, Azzola L, et al. Transcriptional profiling of mouse and human ES cells identifies SLAIN1, a novel stem cell gene. Dev. Biol. 2006; 293:90-103.
Hirst CE, Lim SM, Pereira LA, et al. Expression from a betageo gene trap in the Slain1 gene locus is predominantly associated with the developing nervous system. Int. J. Dev. Biol. 2010; 54:1383-8.
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