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TINP1 Antibody

     
  • 1 - TINP1 Antibody ASC11111
    Western blot analysis of TINP1 in rat brain tissue lysate with TINP1 antibody at (A) 1 and (B) 2 µg/mL.
  • 2 - TINP1 Antibody ASC11111
    Immunohistochemistry of TINP1 in human brain tissue with TINP1 antibody at 5 µg/mL.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E, IHC-P
Primary Accession O95478
Other Accession NP_055701, 7662677
Reactivity Human, Mouse, Rat
Host Chicken
Clonality Polyclonal
Isotype IgY
Calculated MW 30065 Da
Concentration (mg/ml) 1 mg/mL
Conjugate Unconjugated
Application Notes TINP1 antibody can be used for detection of TINP1 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL.
Additional Information
Gene ID 10412
Other Names Ribosome biogenesis protein NSA2 homolog, Hairy cell leukemia protein 1, TGF-beta-inducible nuclear protein 1, NSA2, TINP1
Target/Specificity NSA2;
Reconstitution & Storage TINP1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsTINP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NSA2
Synonyms TINP1
Function Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles (By similarity).
Cellular Location Nucleus, nucleolus.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

TINP1 Antibody: TINP1 (TGF-beta inducible nuclear protein 1), also known as NSA2 (Nop seven-associated 2), is a highly conserved nucleolar protein essential for large ribosomal subunit biogenesis. NSA2 is broadly expressed in human tissues and cultured cell lines, and located in the nucleolus of the cell. It is thought to be involved in cell proliferation and cell cycle regulation.

REFERENCES

Lebreton A, Saveanu C, Decourty L, et al. Nsa2 is an unstable, conserved factor required for the maturation of 27 SB pre-rRNAs. J. Biol. Chem.2006; 281:27099-108.
Zhang H, Ma X, Shi T, et al. NSA2, a novel nucleolus protein regulates cell proliferation and cell cycle. Biochem. Biophys. Res. Commun.2010; 391:651-8.

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