APC3 Antibody

Western blot analysis of APC3 in mouse liver tissue lysate with APC3 antibody at (A) 1 and (B) 2 µg/mL.
Immunohistochemistry of APC3 in rat liver tissue with APC3 antibody at 5 µg/mL.

Western blot analysis of APC3 in mouse liver tissue lysate with APC3 antibody at (A) 1 and (B) 2 µg/mL.

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	WB, E, IHC-P
Primary Accession	P30260
Other Accession	NP_001247, 167466175
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Calculated MW	91867 Da
Concentration (mg/ml)	1 mg/mL
Conjugate	Unconjugated
Application Notes	APC3 antibody can be used for detection of APC3 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL.

Additional Information
Gene ID	996
Other Names	Cell division cycle protein 27 homolog, Anaphase-promoting complex subunit 3, APC3, CDC27 homolog, CDC27Hs, H-NUC, CDC27, ANAPC3, D0S1430E, D17S978E
Target/Specificity	CDC27;
Reconstitution & Storage	APC3 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Precautions	APC3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Protein Information
Name	CDC27
Synonyms	ANAPC3, D0S1430E, D17S978E
Function	Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle (PubMed:18485873). The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (PubMed:18485873). The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins (PubMed:29033132).
Cellular Location	Nucleus. Cytoplasm, cytoskeleton, spindle

Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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Discontinued

Cat# ASC11115

Size:

0.1 mg

Price:

¥ 5,587.00

替代产品:

CDC27 Antibody, CDC27 Antibody, Cdc27 Polyclonal Antibody,