FOXO4 Antibody

Western blot analysis of FOXO4 in HeLa cell lysate with FOXO4 antibody at (A) 0.5 and (B) 1 µg/mL.
Immunocytochemistry of FOXO4 in HeLa cells with FOXO4 antibody at 10 µg/mL.

Western blot analysis of FOXO4 in HeLa cell lysate with FOXO4 antibody at (A) 0.5 and (B) 1 µg/mL.

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	WB, IF, ICC, E
Primary Accession	P98177
Other Accession	NP_005929, 103472003
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Calculated MW	53684 Da
Concentration (mg/ml)	1 mg/mL
Conjugate	Unconjugated
Application Notes	FOXO4 antibody can be used for detection of FOXO4 by Western blot at 0.5 - 1 µg/mL. Antibody can also be used for immunocytochemistry starting at 10 µg/mL. For immunofluorescence start at 20 µg/mL.

Additional Information
Gene ID	4303
Other Names	Forkhead box protein O4, Fork head domain transcription factor AFX1, FOXO4, AFX, AFX1, MLLT7
Target/Specificity	FOXO4;
Reconstitution & Storage	FOXO4 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Precautions	FOXO4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Protein Information
Name	FOXO4
Synonyms	AFX, AFX1, MLLT7
Function	Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity.
Cellular Location	Cytoplasm. Nucleus. Note=When phosphorylated, translocated from nucleus to cytoplasm. Dephosphorylation triggers nuclear translocation. Monoubiquitination increases nuclear localization. When deubiquitinated, translocated from nucleus to cytoplasm
Tissue Location	Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Isoform zeta is most abundant in the liver, kidney, and pancreas

Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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Discontinued

Cat# ASC11152

Size:

0.1 mg

Price:

¥ 5,587.00

替代产品:

FOXO4 Antibody (Center), MLLT7 Antibody (N-term), FOXO4 Antibody (C-term),