癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
ApoA5 Antibody
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, E |
|---|---|
| Primary Accession | E1BT17 |
| Other Accession | XP_417939, 118101989 |
| Reactivity | Human, Chicken |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration (mg/ml) | 1 mg/mL |
| Conjugate | Unconjugated |
| Application Notes | ApoA5 antibody can be used for detection of ApoA5 by Western blot at 1 µg/mL. |
| Gene ID | 419802 |
|---|---|
| Target/Specificity | APOA5; |
| Reconstitution & Storage | ApoA5 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Precautions | ApoA5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
ApoA5 Antibody: Apolipoprotein A4 (also known as ApoA-IV) is a plasma protein that is O-linked glycoprotein after proteolytic processing. ApoA4 is a major constituent of HDL and it also can be found on the surface of newly synthesized chylomicrons. The physiological function of ApoA4 is not completely identified so far, but several evidences from vitro studies indicate that this apolipoprotein involves in several steps of the reverse cholesterol transport pathway, which transports cholesterol from peripheral cells back to the liver.
REFERENCES
Van der Vliet HN, Sammels MG, Leegwater AC, et al. Apolipoprotein A-V: a novel apolipoprotein associated with an early phase of liver regeneration. J. Biol. Chem. 2001; 276: 44512-20
Vu-Dac N, Gervois P, Jakel H, Nowak M, et al. Apolipoprotein A5, a crucial determinant of plasma triglyceride levels, is highly responsive to peroxisome proliferator-activated receptor alpha activators. J. Biol.Chem. 2003; 278:17982-5
Nilsson SK, Christensen S, Raarup MK, et al. Endocytosis of apolipoprotein AV by members of the low density lipoprotein receptor and the Vps10p domain receptor families" J. Biol. Chem. 2008; 283: 25920-7.
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