癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
IFTLD1 Antibody
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- 实验流程
- 背景知识
Application 
| WB, E, IHC-P |
|---|---|
| Primary Accession | Q8N9Z9 |
| Other Accession | NP_001139200, 224593273 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 43408 Da |
| Concentration (mg/ml) | 1 mg/mL |
| Conjugate | Unconjugated |
| Application Notes | IFLTD1 antibody can be used for detection of IFLTD1 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. |
| Gene ID | 160492 |
|---|---|
| Other Names | Lamin tail domain-containing protein 1, Intermediate filament tail domain-containing protein 1, LMNTD1, IFLTD1 |
| Target/Specificity | IFLTD1; At least four isoforms of IFLTD1 are known to exist; this antibody will detect all but isoform 4 |
| Reconstitution & Storage | IFTLD1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Precautions | IFTLD1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | LMNTD1 |
|---|---|
| Synonyms | IFLTD1 |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
IFTLD1 Antibody: The intermediate filament tail domain-containing protein (IFLTD1) was initially identified as a candidate gene for pulmonary adenoma susceptibility 1 gene in mice. Transcripts of the gene were only detected in mouse lung tissue from strains carrying the Pas1-susceptible allele. Expression of different alleles of this gene in lung cancer cell lines resulted in different levels of colony formation in in vitro colony formation assays, suggesting that allelic variants of this gene can modulate growth of human cancer cells.
REFERENCES
Wang M, Lemon WJ, Liu G, et al. Fine mapping and identification of candidate pulmonary adenoma susceptibility 1 genes using advanced intercross lines. Cancer Res. 2003; 63:3317-24.
Wang M, Futamura M, Wang Y, et al. Pasc1 is a candidate for the mouse pulmonary adenoma susceptibility 1 locus. Oncogene 2005; 24:1958-63.
Galbiati F, Pettinicchio A, Dragani TA, et al. Allelic effects of mouse Pas candidate genes in human lung cancer cell lines. Cancer Lett. 244:176-81.
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