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SPATA4 Antibody
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Application 
| WB, IF, E, IHC-P |
|---|---|
| Primary Accession | Q8NEY3 |
| Other Accession | NP_653245, 31543825 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 34751 Da |
| Concentration (mg/ml) | 1 mg/mL |
| Conjugate | Unconjugated |
| Application Notes | SPATA4 antibody can be used for detection of SPATA4 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 20 µg/mL. |
| Gene ID | 132851 |
|---|---|
| Other Names | Spermatogenesis-associated protein 4, Testis and spermatogenesis cell-related protein 2, Testis spermatocyte apoptosis-related gene 2 protein, SPATA4, TSARG2 |
| Target/Specificity | SPATA4; At least two isoforms of SPATA4 are known to exist; this antibody will detect both isoforms. SPATA4 antibody is predicted to not cross-react with SPATA protein family members |
| Reconstitution & Storage | SPATA4 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Precautions | SPATA4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SPATA4 |
|---|---|
| Synonyms | TSARG2 |
| Function | May play a role in apoptosis regulation. |
| Cellular Location | Nucleus. |
| Tissue Location | Highly expressed in testis, the expression is observed precisely in seminiferous tubules |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
SPATA4 Antibody: The spermatogenesis associated protein 4 (SPATA4) protein, also known as TSARG1, is highly expressed in testis, and to a much lower extent in other tissues. SPATA4 contains a highly conserved DUF1042 domain, but no significant homology with any other known protein. SPATA4 is thought to play an important role in the development of cryptorchid testis and is a testis-specific apoptosis candidate oncogene.
REFERENCES
Liu SF, Lu GX, Liu G, et al. Cloning of a full-length cDNA of human testis-specific spermatogenic cell apoptosis inhibitor TSARG2 as a candidate oncogene. Biochem. Biophys. Res. Commun. 2004; 319:32-40
Liu SF, Ai C, Ge ZQ, et al. Molecular cloning and bioinformatic analysis of SPATA4 gene. J. Biochem. Mol. Biol. 2005; 38:739-47.
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