癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
FOXD4L1 Antibody
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, ICC, E |
|---|---|
| Primary Accession | Q9NU39 |
| Other Accession | NP_036316, 18959276 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 43610 Da |
| Concentration (mg/ml) | 1 mg/mL |
| Conjugate | Unconjugated |
| Application Notes | FOXD4L1 antibody can be used for detection of FOXD4L1 by Western blot at 1 µg/mL. Antibody can also be used for immunocytochemistry at 10 µg/ml. |
| Gene ID | 200350 |
|---|---|
| Other Names | Forkhead box protein D4-like 1, FOXD4-like 1, FOXD4L1 |
| Target/Specificity | FOXD4L1; This antibody is predicted to not cross-react with any FOXD4 protein family members |
| Reconstitution & Storage | FOXD4L1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Precautions | FOXD4L1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | FOXD4L1 |
|---|---|
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00089}. |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
FOXD4L1 Antibody: FOXD4L1, also known as FOXD5, is a member of the forkhead/winged-helix (FOX) family of transcription factors with highly conserved FOX DNA-binding domains. Members of the FOX family of transcription factors are regulators of embryogenesis and is thought to play a role in human cancer. FOXD4L1 is a forkhead transcription factor that functions as both a transcriptional activator and repressor and acts upstream of several other neural transcription factors to maintain neural fate, regulate neural plate patterning, and delay the expression of neural differentiation factors.
REFERENCES
Jackson BC, Carpenter C, Nebert DW, et al. Update of human and mouse forkhead box (FOX) gene families. Hum. Genomics 2010; 4:345-52.
Yan B, Neilson KM, and Moody SA. Microarray identification of novel downstream targets of FoxD4L1/D5, a critical component of the neural ectodermal transcriptional network. Dev. Dyn. 2010; 239:3467-80.
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