GDF1 Antibody
- 产品详情
- 实验流程
- 背景知识
Application ![]()
| WB, IF, E |
---|---|
Primary Accession | P27539 |
Other Accession | NP_001483, 110349792 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 39475 Da |
Concentration (mg/ml) | 1 mg/mL |
Conjugate | Unconjugated |
Application Notes | GDF1 antibody can be used for detection of GDF1 by Western blot at 1 - 2 µg/mL. For immunofluorescence start at 20 µg/mL. |
Gene ID | 2657 |
---|---|
Other Names | Embryonic growth/differentiation factor 1, GDF-1, GDF1 |
Target/Specificity | GDF1; GDF1 antibody is predicted to not cross-react with any other members of the growth differentiation factor family. |
Reconstitution & Storage | GDF1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Precautions | GDF1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GDF1 |
---|---|
Function | May mediate cell differentiation events during embryonic development. |
Cellular Location | Secreted. |
Tissue Location | Expressed in the brain. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
GDF1 Antibody: Growth differentiation factors (GDFs) are members of the transforming growth factor (TGF) superfamily that is involved in embryonic development and adult tissue homeostasis. GDF1 was initially identified as a temporally expressed gene in the mouse central nervous system during embryonic development, with only one isoform detected in adult tissues. GDF1 is required for left-right patterning during development and directly interacts with Nodal, another member of the TGF-beta superfamily. It has been suggested that GDF1 regulates the activity and signaling range of Nodal through direct interaction.
REFERENCES
Massague J. 1990. The transforming growth factor-beta family. Ann. Rev. Cell Biol. 6:597-641.
Lee SJ. Expression of growth/differentiation factor 1 in the nervous system: conservation of a bicistronic structure. Proc. Natl. Acad. Sci. USA 1991; 88:4250-4.
Rankin CT, Bunton T, Lawler AM, et al. Regulation of left-right patterning in mice by growth/differentiation factor-1. Nat. Genet. 2000; 24:262-5.
Tanaka C, Sakuma R, Nakamura T, et al. Long-range action of Nodal requires interaction with GDF1. Genes Dev. 2007; 21:3272-82.

终于等到您。ABCEPTA(百远生物)抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息,您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。
如有疑问,联系:0512-88856768 tech-china@abcepta.com.