癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
MOSPD1 Antibody
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IF, E, IHC-P |
|---|---|
| Primary Accession | Q9UJG1 |
| Other Accession | NP_062456, 9506543 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 24086 Da |
| Concentration (mg/ml) | 1 mg/mL |
| Conjugate | Unconjugated |
| Application Notes | MOSPD1 Antibody can be used for detection of MOSPD1 by Western blot at 1 µg/mL. |
| Gene ID | 56180 |
|---|---|
| Other Names | Motile sperm domain-containing protein 1, MOSPD1 |
| Target/Specificity | MOSPD1; |
| Reconstitution & Storage | MOSPD1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. |
| Precautions | MOSPD1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | MOSPD1 |
|---|---|
| Function | Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to- mesenchymal transition (EMT). However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation. |
| Cellular Location | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q8VEL0}; Multi-pass membrane protein. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q8VEL0}; Multi-pass membrane protein |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
MOSPD1 Antibody: The Motile sperm domain-containing protein 1 (MOSPD1) is part of a family of proteins defined by the presence of a major sperm protein (MSP) domain and two transmembrane domains. MOSPD1 codes for a small protein that localizes to the endoplasmic reticulum (ER) and the Golgi apparatus and has been suggested to play a role in the developmental regulation at the switch between mesenchymal and epithelial cells.
REFERENCES
Pall GS, Wallis J, Axton R, et al. A novel transmembrane MSP-containing protein that plays a role in the right ventricle development. Genomics 2004; 84:1051-9.
Thaler R, Rumpler M, Spitzer S, et al. Mospd1, a new player in mesenchymal versus epidermal cell differentiation. J. Cell Physiol. 2011; 226:2505-15.
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