癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
La Crosse Virus Nucleocapsid Antibody
- 产品详情
- 实验流程
- 背景知识
Application 
| E |
|---|---|
| Primary Accession | Q8JPR0 |
| Other Accession | AAM94389, 22212786 |
| Reactivity | Virus |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 26556 Da |
| Concentration (mg/ml) | 1 mg/mL |
| Conjugate | Unconjugated |
| Application Notes | La Crosse virus nucleocapsid antibody can detect 10 ng La Crosse virus nucleocapsid peptide in ELISA at 1 µg/mL. |
| Gene ID | 956556 |
|---|---|
| Other Names | Nucleoprotein, Nucleocapsid protein, Protein N, N |
| Target/Specificity | N; |
| Reconstitution & Storage | Rift Valley Fever Virus Nucleocapsid antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. |
| Precautions | La Crosse Virus Nucleocapsid Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | N |
|---|---|
| Function | Encapsidates the genome protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for transcription and replication. The NC have a helical organization. Seems to participate in the nuclear relocalization of host PABP1, thereby inhibiting host cellular translation. |
| Cellular Location | Virion {ECO:0000250|UniProtKB:P16495}. Note=Located inside the virion, complexed with the viral RNA {ECO:0000250|UniProtKB:P16495} |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
La Crosse Virus Nucleocapsid Antibody: La Crosse virus (LCV) is a single-stranded RNA virus that can cause encephalitis in humans and is transmitted predominantly by mosquitoes. It is often mistaken for herpes simplex encephalitis (1). During human infections, LCV initially presents as a nonspecific summertime illness with fever, headache, nausea, vomiting and lethargy. Death occurs in less than 1% of clinical cases.
REFERENCES
McJunkin JE, de los Reyes EC, Irazuzta JE, et al. La Crosse encephalitis in children. N. Eng. J. Med. 2001; 344:801-7.
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