癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
NAP1L5 Antibody
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IF, E, IHC-P |
|---|---|
| Primary Accession | Q96NT1 |
| Other Accession | NP_715638, 24371268 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 19593 Da |
| Concentration (mg/ml) | 1 mg/mL |
| Conjugate | Unconjugated |
| Application Notes | NAP1L5 antibody can be used for detection of NAP1L5 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL. |
| Gene ID | 266812 |
|---|---|
| Other Names | Nucleosome assembly protein 1-like 5, Down-regulated in liver malignancy, NAP1L5, DRLM |
| Target/Specificity | NAP1L5; NAP1L5 antibody is human, mouse and rat reactive. |
| Reconstitution & Storage | NAP1L5 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. |
| Precautions | NAP1L5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NAP1L5 |
|---|---|
| Synonyms | DRLM |
| Cellular Location | Nucleus. |
| Tissue Location | Predominantly expressed in brain. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
The nucleosome assembly protein 1-like 5 (NAP1L5) protein, also known as DRLM, was initially identified as a possible tumor suppressor gene in hepatocellular carcinoma (1). The NAP1L5 gene is located within the intron of Herc3, and unlike Herc3, is imprinted and highly expressed in regions of the adult mouse brain (2).
REFERENCES
Harada H, Nagai H, Ezura Y, et al. Down-regulation of a novel gene, DRLM, in human liver malignancy from 4q22 that encodes a NAP-like protein. Gene 2002; 296:171-7.
Davies W, Smith RJ, Kelsey G, et al. Expression patterns of the novel imprinted genes Nap1L5 and Peg13 and their non-imprinted host genes in the adult mouse brain. Gene Expr. Patterns 2004; 4:741-7.
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