癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
C18orf42 Antibody
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, E |
|---|---|
| Primary Accession | P0CW23 |
| Other Accession | NP_001138666, 223633927 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 7848 Da |
| Concentration (mg/ml) | 1 mg/mL |
| Conjugate | Unconjugated |
| Application Notes | C18orf42 antibody can be used for the detection of C18orf42 by Western blot at 1 - 2 µg/mL. |
| Gene ID | 642597 |
|---|---|
| Other Names | Putative uncharacterized protein C18orf42, C18orf42 |
| Target/Specificity | C18orf42; C18orf42 antibody is human specific. |
| Reconstitution & Storage | C18orf42 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. |
| Precautions | C18orf42 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | AKAIN1 (HGNC:28285) |
|---|---|
| Synonyms | C18orf42 |
| Function | Protein kinase A (PKA)-binding protein. Binds to type II regulatory subunits of protein kinase A (PKA) and may block the A- kinase anchoring protein (AKAP)-mediated subcellular localization of PKA (PubMed:25653177). |
| Tissue Location | Preferentially expressed in the neural tissues (PubMed:25653177). |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Little is known of the function of the protein encoded by Chromosome 18 open reading frame 18 (C18orf42), but it is preferentially expressed in neuronal tissue (1). It is thought to bind to the cAMP-dependent protein kinase A (PKA) and regulation its interaction with members of the A-kinase anchoring protein (AKAP) family (1).
REFERENCES
Fukuda M and Aizawa Y. Hypothetical gene C18orf42 encodes a novel protein kinase A-binding protein. Genes Cells 2015; 20:267-80.
终于等到您。ABCEPTA（百远生物）抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息，您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。
如有疑问，联系：0512-88856768 tech-china@abcepta.com.
