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>   首页   >   产品   >   一抗   >   癌症   >   ACADVL Antibody (monoclonal) (M01)   

ACADVL Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant ACADVL.

     
  • 1 - ACADVL Antibody (monoclonal) (M01) AT1019a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (35.64 KDa) .
  • 1 - ACADVL Antibody (monoclonal) (M01) AT1019a
    ACADVL monoclonal antibody (M01), clone 5D3 Western Blot analysis of ACADVL expression in Hela S3 NE ( (Cat # AT1019a )
  • 2 - ACADVL Antibody (monoclonal) (M01) AT1019a
    Immunoperoxidase of monoclonal antibody to ACADVL on formalin-fixed paraffin-embedded human heart. [antibody concentration 3 ug/ml]
  • 10 - ACADVL Antibody (monoclonal) (M01) AT1019a
    Detection limit for recombinant GST tagged ACADVL is approximately 0.03ng/ml as a capture antibody.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC, E
Primary Accession P49748
Other Accession NM_000018
Reactivity Human
Host mouse
Clonality monoclonal
Isotype IgG2b Kappa
Clone Names 5D3
Calculated MW 70390 Da
Additional Information
Gene ID 37
Other Names Very long-chain specific acyl-CoA dehydrogenase, mitochondrial, VLCAD, ACADVL, VLCAD
Target/Specificity ACADVL (NP_000009, 345 a.a. ~ 434 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
IHC~~1:100~500
E~~N/A
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsACADVL Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

The protein encoded by this gene is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy. Alternative splicing results in multiple transcript variants encoding different isoforms.

REFERENCES

1.ACAD9, a complex I assembly factor with a moonlighting function in fatty acid oxidation deficiencies.Nouws J, Te Brinke H, Nijtmans LG, Houten SMHum Mol Genet. 2013 Nov 6.2.Mild mitochondrial uncoupling does not affect mitochondrial biogenesis but downregulates pyruvate carboxylase in adipocytes: role for triglyceride content reduction.De Pauw A, Demine S, Tejerina S, Dieu M, Delaive E, Kel A, Renard P, Raes M, Arnould T.Am J Physiol Endocrinol Metab. 2012 May;302(9):E1123-41. Epub 2012 Feb 21.

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