癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
AHNAK Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant AHNAK.
- 产品详情
- 实验流程
Application 
| WB, IP, E |
|---|---|
| Primary Accession | Q09666 |
| Other Accession | NM_024060 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 3G7 |
| Calculated MW | 629101 Da |
| Gene ID | 79026 |
|---|---|
| Other Names | Neuroblast differentiation-associated protein AHNAK, Desmoyokin, AHNAK, PM227 |
| Target/Specificity | AHNAK (NP_076965, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IP~~N/A E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | AHNAK Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
1.Proteomic investigation of the interactome of FMNL1 in hematopoietic cells unveils a role in calcium-dependent membrane plasticity.Han Y, Yu G, Sarioglu H, Caballero-Martinez A, Schlott F, Ueffing M, Haase H, Peschel C, Krackhardt AM.J Proteomics. 2012 Nov 24. pii: S1874-3919(12)00756-7. doi: 10.1016/j.jprot.2012.11.015.2.Ahnak1 interaction is affected by phosphorylation of Ser-296 on Cav?]2.Pankonien I, Otto A, Dascal N, Morano I, Haase H.Biochem Biophys Res Commun. 2012 Apr 4. [Epub ahead of print]3.Ahnak1 abnormally localizes in muscular dystrophies and contributes to muscle vesicle release.Zacharias U, Purfurst B, Schowel V, Morano I, Spuler S, Haase H.J Muscle Res Cell Motil. 2011 Nov 5. [Epub ahead of print]4.The C type natriuretic peptide receptor tethers AHNAK1 at the plasma membrane to potentiate arachidonic acid induced calcium mobilization.Alli AA, Gower WR Jr.Am J Physiol Cell Physiol. 2009 Aug 26. [Epub ahead of print]5.Searching for new biomarkers of bladder cancer based on proteomic analysis.Okusa H, Kodera Y, Oh-Ishi M, MinamidaY, Tsuchida M, Kavoussi N, Matsumoto K, Sato T, Iwamura M, Maeda Y, Baba S.J Electrophoresis 2008 ; 52 : 19
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