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>   首页   >   产品   >   一抗   >   癌症   >   ARMCX1 Antibody (monoclonal) (M01)   

ARMCX1 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant ARMCX1.

     
  • 1 - ARMCX1 Antibody (monoclonal) (M01) AT1197a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.62 KDa) .
  • 1 - ARMCX1 Antibody (monoclonal) (M01) AT1197a
    Western Blot analysis of ARMCX1 expression in transfected 293T cell line by ARMCX1 monoclonal antibody (M01), clone 6E10.

    Lane 1: ARMCX1 transfected lysate (Predicted MW: 49.2 KDa).
    Lane 2: Non-transfected lysate.
  • 10 - ARMCX1 Antibody (monoclonal) (M01) AT1197a
    Detection limit for recombinant GST tagged ARMCX1 is approximately 0.03ng/ml as a capture antibody.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q9P291
Other Accession NM_016608
Reactivity Human
Host mouse
Clonality monoclonal
Isotype IgG3 Kappa
Clone Names 6E11
Calculated MW 49180 Da
Additional info
Gene ID 51309
Other Names Armadillo repeat-containing X-linked protein 1, ARM protein lost in epithelial cancers on chromosome X 1, Protein ALEX1, ARMCX1, ALEX1
Target/Specificity ARMCX1 (NP_057692, 188 a.a. ~ 295 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsARMCX1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas

BACKGROUND

This gene encodes a member of the ALEX family of proteins and may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and two Armadillo (arm) repeats. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members, including ALEX2 and ALEX3, on the X chromosome.

REFERENCES

Human Arm protein lost in epithelial cancers, on chromosome X 1 (ALEX1) gene is transcriptionally regulated by CREB and Wnt/beta-catenin signaling. Iseki H, et al. Cancer Sci, 2010 Jun. PMID 20398052.Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. Otsuki T, et al. DNA Res, 2005. PMID 16303743.The DNA sequence of the human X chromosome. Ross MT, et al. Nature, 2005 Mar 17. PMID 15772651.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039.

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