癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
BGLAP Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant BGLAP.
- 产品详情
- 实验流程
Application 
| WB, IF, E |
|---|---|
| Primary Accession | P02818 |
| Other Accession | NM_199173 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG1 lambda |
| Clone Names | 2D4 |
| Calculated MW | 10963 Da |
| Gene ID | 632 |
|---|---|
| Other Names | Osteocalcin, Bone Gla protein, BGP, Gamma-carboxyglutamic acid-containing protein, BGLAP |
| Target/Specificity | BGLAP (NP_954642, 52 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IF~~1:50~200 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | BGLAP Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Analysis of osteocalcin as a candidate gene for type 2 diabetes (T2D) and intermediate traits in Caucasians and African Americans. Das SK, et al. Dis Markers, 2010 Jan 1. PMID 20592451.Reduced serum total osteocalcin is associated with metabolic syndrome in older men via waist circumference, hyperglycemia, and triglyceride levels. Yeap BB, et al. Eur J Endocrinol, 2010 Aug. PMID 20501596.Evidence for osteocalcin production by adipose tissue and its role in human metabolism. Foresta C, et al. J Clin Endocrinol Metab, 2010 Jul. PMID 20410230.Serum osteocalcin is associated with measures of insulin resistance, adipokine levels, and the presence of metabolic syndrome. Saleem U, et al. Arterioscler Thromb Vasc Biol, 2010 Jul. PMID 20395593.Hepatic osteodystrophy and liver cirrhosis. Goral V, et al. World J Gastroenterol, 2010 Apr 7. PMID 20355242.
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