癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
CCNL1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant CCNL1.
- 产品详情
- 实验流程
Application 
| WB, IF, E |
|---|---|
| Primary Accession | Q9UK58 |
| Other Accession | BC038394 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG1 kappa |
| Clone Names | 1F7-1C5 |
| Calculated MW | 59634 Da |
| Gene ID | 57018 |
|---|---|
| Other Names | Cyclin-L1, Cyclin-L, CCNL1 |
| Target/Specificity | CCNL1 (AAH38394, 1 a.a. ~ 172 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IF~~1:50~200 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | CCNL1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight. Freathy RM, et al. Nat Genet, 2010 May. PMID 20372150.Characterization of cyclin L1 and L2 interactions with CDK11 and splicing factors: influence of cyclin L isoforms on splice site selection. Loyer P, et al. J Biol Chem, 2008 Mar 21. PMID 18216018.Characterization of cyclin L1 as an immobile component of the splicing factor compartment. Herrmann A, et al. FASEB J, 2007 Oct. PMID 17494991.Cyclin L1 (CCNL1) gene alterations in human head and neck squamous cell carcinoma. Muller D, et al. Br J Cancer, 2006 Apr 10. PMID 16598186.Amplification of Cyclin L1 is associated with lymph node metastases in head and neck squamous cell carcinoma (HNSCC). Sticht C, et al. Br J Cancer, 2005 Feb 28. PMID 15700036.
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