癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
CD7 Antibody (monoclonal) (M04)
Mouse monoclonal antibody raised against a full length recombinant CD7.
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IP, E |
|---|---|
| Primary Accession | P09564 |
| Other Accession | BC009293 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2b Kappa |
| Clone Names | 1B8 |
| Calculated MW | 25409 Da |
| Gene ID | 924 |
|---|---|
| Other Names | T-cell antigen CD7, GP40, T-cell leukemia antigen, T-cell surface antigen Leu-9, TP41, CD7, CD7 |
| Target/Specificity | CD7 (AAH09293, 21 a.a. ~ 240 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IP~~N/A E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | CD7 Antibody (monoclonal) (M04) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene encodes a transmembrane protein which is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development.
REFERENCES
CD7 in acute myeloid leukemia: correlation with loss of wild-type CEBPA, consequence of epigenetic regulation. R?hrs S, et al. J Hematol Oncol, 2010 Apr 14. PMID 20398252.Expression of the leukemic prognostic marker CD7 is linked to epigenetic modifications in chronic myeloid leukemia. Rogers SL, et al. Mol Cancer, 2010 Feb 22. PMID 20175919.Frequent CD7 antigen loss in aggressive natural killer-cell leukemia: a useful diagnostic marker. Yoo EH, et al. Korean J Lab Med, 2009 Dec. PMID 20046078.Twist2 regulates CD7 expression and galectin-1-induced apoptosis in mature T-cells. Koh HS, et al. Mol Cells, 2009 Dec 31. PMID 19937140.Glycodelin A triggers T cell apoptosis through a novel calcium-independent galactose-binding lectin activity. SundarRaj S, et al. Mol Immunol, 2009 Oct. PMID 19683346.
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