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>   首页   >   产品   >   一抗   >   癌症   >   CIAPIN1 Antibody (monoclonal) (M01)   

CIAPIN1 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant CIAPIN1.

     
  • 1 - CIAPIN1 Antibody (monoclonal) (M01) AT1535a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.96 KDa) .
  • 1 - CIAPIN1 Antibody (monoclonal) (M01) AT1535a
    CIAPIN1 monoclonal antibody (M01), clone 5G8. Western Blot analysis of CIAPIN1 expression in PC-12((Cat # AT1535a )
  • 1 - CIAPIN1 Antibody (monoclonal) (M01) AT1535a
    CIAPIN1 monoclonal antibody (M01), clone 5G8 Western Blot analysis of CIAPIN1 expression in HepG2 ( (Cat # AT1535a )
  • 1 - CIAPIN1 Antibody (monoclonal) (M01) AT1535a
    CIAPIN1 monoclonal antibody (M01), clone 5G8. Western Blot analysis of CIAPIN1 expression in Raw 264.7((Cat # AT1535a )
  • 10 - CIAPIN1 Antibody (monoclonal) (M01) AT1535a
    Detection limit for recombinant GST tagged CIAPIN1 is approximately 1ng/ml as a capture antibody.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q6FI81
Other Accession NM_020313
Reactivity Human, Mouse, Rat
Host mouse
Clonality monoclonal
Isotype IgG1 Lambda
Clone Names 5G8
Calculated MW 33582 Da
Additional Information
Gene ID 57019
Other Names Anamorsin {ECO:0000255|HAMAP-Rule:MF_03115}, Cytokine-induced apoptosis inhibitor 1 {ECO:0000255|HAMAP-Rule:MF_03115}, Fe-S cluster assembly protein DRE2 homolog {ECO:0000255|HAMAP-Rule:MF_03115}, CIAPIN1 {ECO:0000255|HAMAP-Rule:MF_03115}
Target/Specificity CIAPIN1 (NP_064709, 266 a.a. ~ 367 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
E~~N/A
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCIAPIN1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

CIAPIN1 is a cytokine-induced inhibitor of apoptosis with no relation to apoptosis regulatory molecules of the BCL2 (MIM 151430) or CASP (see MIM 147678) families. Expression of CIAPIN1 is dependent on growth factor stimulation (Shibayama et al., 2004 [PubMed 14970183]).

REFERENCES

A newly identified essential complex, Dre2-Tah18, controls mitochondria integrity and cell death after oxidative stress in yeast. Vernis L, et al. PLoS One, 2009. PMID 19194512.CIAPIN1 inhibits the growth and proliferation of clear cell renal cell carcinoma. He L, et al. Cancer Lett, 2009 Apr 8. PMID 19081179.Dre2, a conserved eukaryotic Fe/S cluster protein, functions in cytosolic Fe/S protein biogenesis. Zhang Y, et al. Mol Cell Biol, 2008 Sep. PMID 18625724.[Reversal of multidrug resistance of gastric cancer cells by down-regulation of CIAPIN1 with CIAPIN1 siRNA] Li X, et al. Mol Biol (Mosk), 2008 Jan-Feb. PMID 18389626.Adenovirus-delivered CIAPIN1 small interfering RNA inhibits HCC growth in vitro and in vivo. Li X, et al. Carcinogenesis, 2008 Aug. PMID 18299278.

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