癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
COPS2 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant COPS2.
- 产品详情
- 实验流程
Application 
| WB, IF |
|---|---|
| Primary Accession | P61201 |
| Other Accession | NM_004236 |
| Reactivity | Human, Mouse, Rat |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 4B12 |
| Calculated MW | 51597 Da |
| Gene ID | 9318 |
|---|---|
| Other Names | COP9 signalosome complex subunit 2, SGN2, Signalosome subunit 2, Alien homolog, JAB1-containing signalosome subunit 2, Thyroid receptor-interacting protein 15, TR-interacting protein 15, TRIP-15, COPS2, CSN2, TRIP15 |
| Target/Specificity | COPS2 (NP_004227, 344 a.a. ~ 443 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IF~~1:50~200 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | COPS2 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.Regulation of the anaphase-promoting complex by the COP9 signalosome. Kob R, et al. Cell Cycle, 2009 Jul 1. PMID 19535905.The coregulator Alien. Papaioannou M, et al. Nucl Recept Signal, 2007 Nov 30. PMID 18174916.Association of SAP130/SF3b-3 with Cullin-RING ubiquitin ligase complexes and its regulation by the COP9 signalosome. Menon S, et al. BMC Biochem, 2008 Jan 3. PMID 18173839.Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.
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