癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
DDX6 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant DDX6.
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IHC, E |
|---|---|
| Primary Accession | P26196 |
| Other Accession | BC065007 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG1 kappa |
| Clone Names | 3D2 |
| Calculated MW | 54417 Da |
| Gene ID | 1656 |
|---|---|
| Other Names | Probable ATP-dependent RNA helicase DDX6, ATP-dependent RNA helicase p54, DEAD box protein 6, Oncogene RCK, DDX6, HLR2, RCK |
| Target/Specificity | DDX6 (AAH65007, 1 a.a. ~ 483 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IHC~~1:100~500 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | DDX6 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing.
REFERENCES
1.DDX6 localizes to nuage structures and the annulus of mammalian spermatogenic cells.Kawahara C, Yokota S, Fujita HHistochem Cell Biol. 2013 Oct 20.2.The DEAD-box RNA Helicase DDX6 is Required for Efficient Encapsidation of a Retroviral Genome.Yu SF, Lujan P, Jackson DL, Emerman M, Linial ML.PLoS Pathog. 2011 Oct;7(10):e1002303. Epub 2011 Oct 13.3.Rck/p54 interacts with APP mRNA as part of a multi-protein complex and enhances APP mRNA and protein expression in neuronal cell lines.Broytman O, Westmark PR, Gurel Z, Malter JS.Neurobiol Aging. 2008 Mar 28 [Epub ahead of print]
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