癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
DEAF1 Antibody (monoclonal) (M06)
Mouse monoclonal antibody raised against a full length recombinant DEAF1.
- 产品详情
- 实验流程
Application 
| WB, IF |
|---|---|
| Primary Accession | O75398 |
| Other Accession | NM_021008 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG2b Kappa |
| Clone Names | 3E7 |
| Calculated MW | 59327 Da |
| Gene ID | 10522 |
|---|---|
| Other Names | Deformed epidermal autoregulatory factor 1 homolog, Nuclear DEAF-1-related transcriptional regulator, NUDR, Suppressin, Zinc finger MYND domain-containing protein 5, DEAF1, SPN, ZMYND5 |
| Target/Specificity | DEAF1 (NP_066288.2, 133 a.a. ~ 222 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 IF~~1:50~200 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | DEAF1 Antibody (monoclonal) (M06) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Aire regulates the expression of differentiation-associated genes and self-renewal of embryonic stem cells. Gu B, et al. Biochem Biophys Res Commun, 2010 Apr 2. PMID 20226168.Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes. Yip L, et al. Nat Immunol, 2009 Sep. PMID 19668219.Functional analysis of the osteoarthritis susceptibility-associated GDF5 regulatory polymorphism. Egli RJ, et al. Arthritis Rheum, 2009 Jul. PMID 19565498.Deaf-1 regulates epithelial cell proliferation and side-branching in the mammary gland. Barker HE, et al. BMC Dev Biol, 2008 Oct 1. PMID 18826651.Gender-specific decrease in NUDR and 5-HT1A receptor proteins in the prefrontal cortex of subjects with major depressive disorder. Szewczyk B, et al. Int J Neuropsychopharmacol, 2009 Mar. PMID 18561871.
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