癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
DNAJB4 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant DNAJB4.
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, E |
|---|---|
| Primary Accession | Q9UDY4 |
| Other Accession | BC034721 |
| Reactivity | Human |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG1 kappa |
| Clone Names | 1H2-3G4 |
| Calculated MW | 37807 Da |
| Gene ID | 11080 |
|---|---|
| Other Names | DnaJ homolog subfamily B member 4, Heat shock 40 kDa protein 1 homolog, HSP40 homolog, Heat shock protein 40 homolog, Human liver DnaJ-like protein, DNAJB4, DNAJW, HLJ1 |
| Target/Specificity | DNAJB4 (AAH34721, 1 a.a. ~ 337 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | DNAJB4 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
DNAJB4 belongs to the evolutionarily conserved DNAJ/HSP40 protein family. For background information on the DNAJ family, see MIM 608375.
REFERENCES
Tumor suppressor HLJ1 binds and functionally alters nucleophosmin via activating enhancer binding protein 2alpha complex formation. Chang TP, et al. Cancer Res, 2010 Feb 15. PMID 20145123.Curcumin inhibits lung cancer cell invasion and metastasis through the tumor suppressor HLJ1. Chen HW, et al. Cancer Res, 2008 Sep 15. PMID 18794131.A new tumor suppressor DnaJ-like heat shock protein, HLJ1, and survival of patients with non-small-cell lung carcinoma. Tsai MF, et al. J Natl Cancer Inst, 2006 Jun 21. PMID 16788156.A member of the heat shock protein 40 family, hlj1, binds to the carboxyl tail of the human mu opioid receptor. Ancevska-Taneva N, et al. Brain Res, 2006 Apr 7. PMID 16542645.The transcriptional factor YY1 upregulates the novel invasion suppressor HLJ1 expression and inhibits cancer cell invasion. Wang CC, et al. Oncogene, 2005 Jun 9. PMID 15782117.
终于等到您。ABCEPTA（百远生物）抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息，您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。
如有疑问，联系：0512-88856768 tech-china@abcepta.com.
