癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
DNAJC10 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant DNAJC10.
- 产品详情
- 实验流程
Application 
| WB, E |
|---|---|
| Primary Accession | Q8IXB1 |
| Other Accession | NM_018981 |
| Reactivity | Human, Mouse, Rat |
| Host | mouse |
| Clonality | monoclonal |
| Isotype | IgG1 Kappa |
| Clone Names | 3A8 |
| Calculated MW | 91080 Da |
| Gene ID | 54431 |
|---|---|
| Other Names | DnaJ homolog subfamily C member 10, 184-, Endoplasmic reticulum DNA J domain-containing protein 5, ER-resident protein ERdj5, ERdj5, Macrothioredoxin, MTHr, DNAJC10, ERDJ5 |
| Target/Specificity | DNAJC10 (NP_061854, 688 a.a. ~ 793 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 E~~N/A |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | DNAJC10 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Meckel-Gruber syndrome protein MKS3 is required for endoplasmic reticulum-associated degradation of surfactant protein C. Wang M, et al. J Biol Chem, 2009 Nov 27. PMID 19815549.ERdj5 sensitizes neuroblastoma cells to endoplasmic reticulum stress-induced apoptosis. Thomas CG, et al. J Biol Chem, 2009 Mar 6. PMID 19122239.ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER. Ushioda R, et al. Science, 2008 Jul 25. PMID 18653895.ERdj4 and ERdj5 are required for endoplasmic reticulum-associated protein degradation of misfolded surfactant protein C. Dong M, et al. Mol Biol Cell, 2008 Jun. PMID 18400946.Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. Otsuki T, et al. DNA Res, 2005. PMID 16303743.
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