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>   首页   >   产品   >   一抗   >   信号转导   >   ERMAP Antibody (monoclonal) (M01)   

ERMAP Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant ERMAP.

     
  • 1 - ERMAP Antibody (monoclonal) (M01) AT1943a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
  • 1 - ERMAP Antibody (monoclonal) (M01) AT1943a
    ERMAP monoclonal antibody (M01), clone 6F8 Western Blot analysis of ERMAP expression in HeLa ( (Cat # AT1943a )
  • 10 - ERMAP Antibody (monoclonal) (M01) AT1943a
    Detection limit for recombinant GST tagged ERMAP is approximately 0.1ng/ml as a capture antibody.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q96PL5
Other Accession NM_001017922
Reactivity Human
Host mouse
Clonality monoclonal
Isotype IgG2a Kappa
Clone Names 6F8
Calculated MW 52605 Da
Additional Information
Gene ID 114625
Other Names Erythroid membrane-associated protein, hERMAP, Radin blood group antigen, Scianna blood group antigen, ERMAP, RD, SC
Target/Specificity ERMAP (NP_001017922, 376 a.a. ~ 475 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
E~~N/A
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsERMAP Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

The protein encoded by this gene is a cell surface transmembrane protein that may act as an erythroid cell receptor, possibly as a mediator of cell adhesion. Polymorphisms in this gene are responsible for the Scianna/Radin blood group system. Two transcript variants encoding the same protein have been found for this gene.

REFERENCES

The polymorphism nt 76 in exon 2 of SC is more frequent in whites than in blacks. Fuchisawa A, et al. Immunohematology, 2009. PMID 19856728.[Expression of human ermap gene in umbilical cord blood mononuclear cells during differentiation and development towards erythroid lineage] Lin LD, et al. Zhongguo Shi Yan Xue Ye Xue Za Zhi, 2008 Apr. PMID 18426659.The DNA sequence and biological annotation of human chromosome 1. Gregory SG, et al. Nature, 2006 May 18. PMID 16710414.SCER and SCAN: two novel high-prevalence antigens in the Scianna blood group system. Flegel WA, et al. Transfusion, 2005 Dec. PMID 16371048.ABO, Rh, MNS, Duffy, Kidd,Yt, Scianna, and Colton blood group systems in indigenous Chinese. Yan L, et al. Immunohematology, 2005. PMID 15783300.

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